Bitter Melon (Momordica charantia L.) Supplementation Has No Effect on Hypercholesterolemia and Atherosclerosis in Mice

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Effects of Momordica charantia (Bitter Melon) on Ischemic Diabetic Myocardium.

Objective: A rat model is here used to test a hypothesis that Momordica charantia (Bitter melon (BM)) extract favorably alters processes in cardiovascular tissue and is systemically relevant to the pathophysiology of type 2 diabetes (T2DM) and related cardiovascular disease. Methods: Male Lean and Zucker Obese (ZO) rats were gavage-treated for six weeks with 400 mg/kg body weight bitter melon (...

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In vivo antitumor activity of the bitter melon (Momordica charantia).

The in vivo antitumor activity of a crude extract from the bitter melon (Momordica charantia) was determined. The extract inhibited tumor formation in CBA/H mice which had been given i.p. injections of 1.0 X 10(5) CBA/Dl tumor cells (77% of the untreated mice with tumors versus 33% of the treated mice with tumors after 6 weeks). The extract also inhibited tumor formation in DBA/2 mice which had...

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Bio-active compounds of bitter melon genotypes (Momordica charantia L.) in relation to their physiological functions

Background: Bitter Melon (Momordica charantia L) is one of the most popular cooked vegetables in many Asian countries. Its experimental use in mice has indicated improvement in glucose tolerance against Type II diabetes and reduction in blood cholesterol. However, it has not been proven which alkaloids, polypeptides, or their combinations in the Bitter Melon extract are responsible for the medi...

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Inheritance of gynoecism in bitter gourd (Momordica charantia L.).

The inheritance of sex expression in cucumber (Cucumis sativus) and other cucurbits is well documented; however, the genetics of female sex (gynoecism) expression in bitter gourd (Momordica charantia) has not been described. Inheritance of gynoecism in bitter gourd was studied in a 100% gynoecious line (Gy263B). The F(2) and testcross segregation data revealed that gynoecism in Gy263B is under ...

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Genetic Divergence Studies in Bitter Gourd (Momordica charantia L.)

A study was conducted during Zaid 2005, in Uttar Pradesh, India, to evaluate the nature and magnitude of genetic divergence in 30 bitter gourd genotypes. Results revealed the presence of wide genetic diversity. The genotypes were grouped into 6 clusters based on Mahalanobis D statistics using Tocher's 2 method. The clustering pattern of genotypes revealed that the genetic diversity was independ...

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ژورنال

عنوان ژورنال: Current Developments in Nutrition

سال: 2020

ISSN: 2475-2991

DOI: 10.1093/cdn/nzaa148